Porokeratosis is a group of skin conditions in which there is abnormal keratinisation. The skin lesions that result are dry and atrophic, with a well-defined ridge-like hyperkeratotic border called a cornoid lamella (best seen on dermoscopy).
Introduction The term porokeratosis refers to skin lesions with a thinned centre surrounded by a ridge-like border called the cornoid lamella. They arise from clones of cells with varying degrees of dysplasia. There are a number of different types of porokeratoses, those best defined are described below.
Porokeratosis is a unique genodermatosis inherited by an autosomal dominant trait.( 1 ) It is characterized by hyperkeratotic lesions with atrophic center and raised wall-like border, which histologically show the classical cornoid lamella.Porokeratosis, a genodermatosis with disorder of keratinization, is characterized clinically by annular plaques with a distinct peripheral keratotic ridge and histologically by the cornoid lamella ( 1 ).Histology of porokeratosis Scanning power view of porokeratosis reveals a hyperkeratotic lesion with a discrete parakeratotic column at the margin, or two if the whole lesion is represented (Figure 1). The diagnostic feature is the presence of a cornoid lamella which represents the clinically visible raised margin of the lesion.
Porokeratosis have a way of making the skin look unsightly. This is the reason many individuals do not delay in getting rid of it. It can also be considerably painful. There is also the fear that porokeratosis can lead to cancer. Though this fear is not completely confirmed, it is however safe to get rid of the skin condition on time before the unexpected happens.
Porokeratosis is a specific disorder of keratinization that is characterized histologically by the presence of a cornoid lamella, a thin column of closely stacked, parakeratotic cells extending through the stratum corneum with a thin or absent granular layer.: 532 1 Types 2 Genetics.
Discussion. Porokeratoma is a recently described type of acanthoma containing the characteristic feature of porokeratosis: The cornoid lamella.(1,2) It usually appears as a tumor-like lesion in patients without personal or familiar history of porokeratosis and without immunosuppressive conditions.() The most frequent locations are extremities, followed by head and neck, chest, buttocks, and.
Porokeratosis (PK) is an uncommon disorder of epidermal keratinization characterized by the appearance of one or more atrophic patches surrounded by a unique ridge-like border, histologically termed a cornoid lamella (1). Porokeratosis (PK), first described in 1983, is a chronic parakeratotic skin disorder.
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Porokeratosis represents a heterogenous group of disorders characterized by the histologic finding of a cornoid lamella. Numerous variants of porokeratosis have been described including disseminated superficial actinic porokeratosis, plaque type or porokeratosis of Mibelli, porokeratosis plantaris, palmaris, et disseminata, linear porokeratosis, punctate porokeratosis, 1 and less commonly.
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Punctate porokeratosis is a skin condition that appears in adulthood as many, tiny, ridgelike bumps on the palms of the hands and soles of the feet. These bumps may slowly spread over the skin and usually do not cause symptoms, though they sometimes cause itching or discomfort while walking.
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